Title : Chronic Pancreatitis - ECAB
Format : Kindle Edition
Pages : 232 pages
Publisher : Pramod Kumar Garg
Language : English

Chronic pancreatitis CP is defined as a continuous or recurrent inflammatory disease of the pancreas characterized by progressive and irreversible morphological changes It typically causes pain and permanent impairment of pancreatic function In chronic pancreatitis areas of focal necrosis are typically associated with perilobular and intralobular fibrosis of the parenchyma by stone formation in the pancreatic duct and by the development of pseudocysts Late in the course of the disease a progressive loss of endocrine and exocrine function occurs In the past chronic pancreatitis was considered to be mostly associated with chronic alcohol abuse During the past 2 decades idiopathic chronic pancreatitis and over hereditary pancreatitis have been recognized as distinct disease entities Usually the diagnosis is made by a combination of imaging procedures such as ultrasound and endoscopic retrograde cholangiopancreatography and exocrine and endocrine function tests Therapy is presently restricted to symptom control for the lack of a causal treatment strategy Thirty to sixty percent of all patients develop disease associated complications such as persistent pain strictures of the common bile duct or pancreatic duct stones that may reuire either endoscopic or surgical treatment